AFC NORTH
Don't lose a major contributor.
AFC SOUTH
AFC WEST
DALLAS — Anthony Hitchens, who started all 16 games at middle linebacker last year but can play all three positions, broke a bone in his right knee against Oakland.
NEW YORK GIANTS — Scary but maybe not too serious, star WR Odell Beckham Jr. went up for a high pass against Cleveland and was hit directly on his knee. Turned out to be no structural damage. But Giants lost DT Jay Bromley (left knee), who was having great camp.
ATLANTA — Standout RB Devonta Freeman spent two weeks in concussion protocol and missed the last three preseason games. Freeman is expected to be ready to play in the regular season opener at Chicago, but WR Devin Fuller will miss the season with a knee injury. It is the second straight year he has had a season-ending injury before playing a game.
NEW ORLEANS — The Saints will start the season without LT Terron Armstead (offseason shoulder surgery) and starting CB Delvin Breaux (surgery in mid-August to repair stress fracture in his left leg). DT Nick Fairley was ruled out for the season with a heart condition during the summer.
DENVER — A bunch of nagging ones, but the main longer-term problem was backup QB Paxton Lynch hurting his right shoulder. Strong safety T.J. Ward pulled his right hamstring early in camp and missed the entire preseason, endangering his roster spot.
ARIZONA — Does GM Steve Keim's torn ACL count? Special teams took the biggest hit because rookie T.J. Logan was expected to return punts and kicks but is out at least eight weeks, and maybe for the season, with a broken wrist.
PHILADELPHIA — Relatively unharmed, the Eagles' backup QB Nick Foles hasn't played in any preseason games because of an elbow injury.
HOUSTON — Obviously, with the damage in Houston from Hurricane Harvey, the Texans have far greater concerns. They did lose WR Will Fuller, who broke his collarbone early in camp.
WASHINGTON — The Redskins were betting on a career revitalization from Cleveland's 2011 first-round pick Phil Taylor after two years out of the NFL because of knee injuries. The DT tore his left quadriceps tendon and is out for the season.
GREEN BAY — One of the luckier squads, with only rookies LB Vince Biegel and DT Montravious Adams being hobbled.
JACKSONVILLE — The Jaguars' only major injury was to long snapper Carson Tinker, who tore a knee ligament during a non-contact drill in training camp and had season-ending surgery.
BUFFALO — Both starting QB Tyrod Taylor and veteran reserve T.J. Yates wound up in the NFL's concussion protocol. Starting  LT Cordy Glenn did not play a preseason game because of nagging soreness in his left foot.
NFC EAST
OAKLAND — A relatively seamless summer, with the most notable injuries to reserve offensive lineman Denver Kirkland (leg) and backup safety Keith McGill (foot). Uncertainty surrounded first-round pick Gareon Conley since minicamp in June when he hurt his shin, but he's expected back for the opener.
INDIANAPOLIS — No Luck, as in Andrew Luck. The star quarterback hasn't practiced after having offseason surgery on his throwing shoulder. Add in starting center Ryan Kelly (foot) going down and needing surgery, and top cornerback Vontae Davis injuring his groin in Week 3 of the preseason and it doesn't look good in Indy.
TAMPA BAY — The Bucs escaped relatively unscathed, with perhaps the most notable issue a right shin laceration suffered in practice that sidelined CB Brent Grimes for the preseason.
MIAMI — When quarterback Ryan Tannehill took a misstep on a run and injured his knee, coach Adam Gase turned to Jay Cutler, with whom he has a successful history. Cutler came out of the broadcast booth to join the Dolphins, who have had a tough summer. Rookie Raekwon McMillan (right ACL),Cheap China Jerseys, projected to start at middle linebacker, is also out for the season; starting G Ted Larsen is expected to miss much of it with a torn right biceps, and No. 3 cornerback Tony Lippett tore his Achilles tendon during practice.
KANSAS CITY — A big one: The Chiefs lost starting RB Spencer Ware (right knee ligaments) for the season. But they do have depth there, particularly with the sharp work of rookie Kareem Hunt so far.
CHICAGO — A weak team to start with, Chicago has a big hole at receiver with Camn Meredith suffering a season-ending knee injury. He could have been the Bears' top wideout.
Several teams failed in their mission this summer, although a few of them should be able to survive the loss (or losses). Others must be wondering if it pays to have regulars see the field at all before September.
NEW YORK JETS — The major injury was WR Quincy Enunwa, who sustained a bulging disk in his neck after f