"You can't turn it over twice. Can't turn it over, one for a touchdown and the other in that situation."
Tandy's momentum carried him into the end zone, giving the Bucs the ball on their 20. They were able to run out the clock.
Hargreaves had a hand in both pickoffs.
The Chargers (5-7) were trying to get back to .500 for the first time since Week 2. They remain buried in the AFC West basement.
Rivers threw two second-half interceptions, including Lavonte David's pick-6.

Tampa Bay also lost WR Adam Humphries with a concussion and tight end Luke Stocker with an ankle injury,Cheap Sharks Jerseys.
"We've had a handful like this, not necessarily exactly losing them this way, but we have had our chances to win and we haven't gotten it done," Rivers said.
Bosa came off late in the game, appearing to slightly favor his left leg. He returned a few plays later. Coach Mike McCoy refused to say what the problem was.
WINNING DRIVE
"We're having fun, and when you have fun good things happen," rookie cornerback Vernon Hargreaves said. "Hopefully we can keep this streak going and see where it takes us."
In his last home game, Rivers was intercepted four times in the fourth quarter of a 31-24 loss to Miami.
After giving up the pick-6, Rivers came right back and led a drive capped by a nice 40-yard touchdown toss to Williams for a 21-17 lead. Rivers also threw a 35-yard touchdown pass to Inman on the game's first possession.
Jameis Winston threw a go-ahead, 12-yard touchdown pass to Cameron Brate midway through the fourth quarter and Keith Tandy intercepted Philip Rivers in the end zone with 2:56 left to give the Tampa Bay Buccaneers their fourth straight victory, 28-21 victory against San Diego on Sunday.
After Winston's go-ahead TD pass to Brate and a 2-point conversion pass to Mike Evans, Rivers had the Chargers on the move in the final minutes. Hargreaves hollered out what route to look for. Tandy got in front of a pass to Dontrelle Inman along the right  sideline and picked it off.
"I've been here for five years and this is the first time we've been playing meaningful football in December, so I can't lie to you, it is a great feeling," Tandy said. "But we also know we have a lot of work to do, so we'll take 24 hours to enjoy it and get back to work."
The Bucs (7-5) pulled into a tie with Atlanta atop the NFC South.
BOSA WATCH
INJURIES
Chargers rookie defensive end Joey Bosa sacked Winston for a 12-yard loss on second-and-10 from the San Diego 15 late in the first half. Jacquizz Rodgers got 14 back on the next play, but the Bucs had to try a 31-yard field goal and Roberto Aguayo pushed it wide right.
SAN DIEGO (AP) — The Tampa Bay Buccaneers, so woeful for so long,Cheap Jerseys For Sale, are doing everything they can to prove they're for real.
"We didn't have the energy we had the last couple of weeks. So that's all we kept talking about,Cheap NFL Jerseys," Tandy said. "You could hear guys going, 'Let's get the energy back. Let's get the energy back and let's keep punching.' "
Tampa Bay wide receiver Cecil Shorts III was taken off the field on a cart after sustaining a knee injury on a hard hit by San Diego's Jahleel Addae following a catch on the Bucs' first possession. Shorts was tended to for a few minutes and then put on the cart. The entire Buccaneers team came out near the cart,Cheap NFL Jerseys Wholesale, and several of the players slapped hands with the wide receiver. Shorts pumped a fist toward his teammates as he was driven off.
Bosa has 5? sacks. He might have had more by now, but he missed all of training camp in a nasty contract spat with management, then hurt a hamstring that cost him the first four games.
He tipped the ball that David plucked out of the air and returned 15 yards for a 17-14 lead late in the third quarter.
Tandy said the defense made adjustments at halftime and came out fired up.
Since winning the Super Bowl here in January 2003 with a rout of the Oakland Raiders, the Bucs have been back to the playoffs only twice,Wholesale NFL Jerseys, losing in the wild-card round both times. They've missed the playoffs the last eight years.
Winston was 20 of 30 for 280 yards, with one TD and one pickoff.
Winston was intercepted by Casey Hayward on Tampa Bay's first possession, but Josh Lambo was wide left on a 53-yard field goal try. Winston then led the Bucs on a drive capped by Doug Martin's 2-yard touchdown run on a great second effort.